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Bio-availability of Nano-Oxygen in Pure Water
 
Bio-availability of oxygenated water is the effectiveness of the oxygen and water to become bio-active after absorption into the bloodstream and measured by the  percentage of its distribution  to target and effector cells as well as the ratio of metabolization. The criteria for oral bioavailability are that the there are  not more than 5 hydrogen donors (OH and NH groups) and no more the 10 hydrogen bond acceptors (notably N and O), where the total molecular weight is under 500 and LogP (Partition Coefficient) is under 5m which is a standard for solubility in solvents. 
 
Oxygen delivery is  normally through a highly vascularized mucous membrane, such as the digestive tract or sublingually allowing more direct access path to blood circulation. The overall absorption potential is always influenced by the preparation and delivery medium. In oxygenated water, only Nano-oxygen physically bonded to the water can accomplish cellular responsiveness and bio-transference.

When most people think about oxygen delivery they naturally think of oxygen for breathing but that is only a part of the process of Bio-oxygenation. Oxygen is delivered on the cellular level 90% through respiration, 2% through the skin and 8% through ionic exchange of nutrients and internal process including the stomach and digestive system. Otto Warburg, the recipient of the Nobel Prize in 1931 and again in 1944 for his discovery of oxygen and hydrogen transferring enzymes said, "Cancer has only one prime cause. It is the replacement of normal oxygen respiration of the body’s cells by an anaerobic cell (i.e. oxygen deficiency).

Professor and Doctor of Medicine, Nasser Drakhsan of Heinrich Heine University, Dusseldorf, Germany was influenced by the cardiovascular surgeon A. Pakdaman in 1967 to research the use of oxygen as a therapy. Dr. Pakdaman found that "oral oxygen is absorbed by diffusion and osmosis through the cells in the stomach and intestines and reaches blood circulation through the portal vein. Such additional oxygen can perform all the same functions as the oxygen absorbed through the lungs. Energies are increased and the quality of life can be improved."